Tag Archives: NMR

Slinn Pickings

Calculations correct natural product structure

November 15, 2012 – 11:03 pm

Calculations correct natural product structure | Chemistry World - US chemists have used NMR prediction calculations to correct the structure of a complex natural product, aquatolide. The work emphasises the power of this burgeoning technique to challenge and inform experimental structure determination.(10.1021/ja3089394)

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Slinn Pickings

3D target: Membrane protein structure

November 15, 2012 – 9:03 am

3D target: Membrane protein structure - The three-dimensional structure of a complete, unmodified G-protein-coupled receptor in its native, membrane environment under physiological conditions has been obtained NMR spectroscopy.(10.1038/nature11580)

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Slinn Pickings

Amyloid-beta peptide behind Alzheimer’s: Hydrogen bonds analyzed for first time

November 6, 2012 – 9:03 pm

Amyloid-beta peptide behind Alzheimer's: Hydrogen bonds analyzed for first time - Using solid-state nuclear magnetic resonance (NMR) spectroscopy, researchers have managed to analyze hydrogen bonds in tiny fibrils of Amyloid-beta peptide , which is considered a probable cause of Alzheimer's disease.(10.1002/anie.201203595)

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