Tag Archives: drugs

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New antimalarial drug class resists resistance | Chemistry World

  • New antimalarial drug class resists resistance | Chemistry World - A new class of antimalarial drugs that is effective across various stages of the malaria parasite’s lifecycle has been developed by an international research team. Early indications also show that it may take longer for the parasite to develop resistance to the new molecules than it has for existing drugs targeting the same pathway.(10.1126/scitranslmed.3005029)
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    Specialised germanium surface as universal protein adapter

  • Specialised germanium surface as universal protein adapter - Researchers at the Ruhr Universität Bochum have developed a new method for attaching proteins to the surface of germanium crystals -- for the first time also membrane proteins. This enables time-resolved tracking of the interactions between molecules using infrared spectroscopy in a way that is accurate down to atomic resolution. The method is applied in the EU project "Kinetics for Drug Discovery, K4DD," in which scientists explore the interplay of drugs and their interaction partners. With the new technology, the researchers can also study so-called G-protein-coupled receptors, which are the site of action for many drugs.(10.1021/ja400253p)
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    Analytical trick accelerates protein studies

  • Analytical trick accelerates protein studies - Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.(10.1038/nmeth.2378)
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