Tag Archives: AFM

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Coral animal chemical structures solved | Chemistry World

Coral animal chemical structures solved | Chemistry World - A combination of atomic force microscopy (AFM) and computational techniques have been used to solve the unusual structures of two natural products from the Arctic coral-like animal, Thuiaria breitfussi.(10.1002/anie.201203960)

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Watching single nanoparticles at work

Watching single nanoparticles at work - By shining laser light on the modified tip of an atomic force microscope (AFM), researchers in Germany and the Netherlands have been able to watch a catalytic reaction in real time, zoomed right in to the nanoscale. The technique combines AFM with Raman spectroscopy, using the silver-coated AFM tip to boost the reaction’s Raman signal while also acting as the catalyst. Using this hybrid approach, the researchers could follow the catalytic conversion of reactants into products with a spatial resolution of just a few nanometres.(10.1038/NNANO.2012.131)

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Filming the roundabout production of cells’ chemical fuel

  • Filming the roundabout production of cells' chemical fuel - Japanese researchers have used a high-speed atomic force microscopy (AFM) to shoot a movie of the tiny rotating enzyme that produces the chemical fuel for cells. There are plenty of still pictures of ATPase, the enzyme that synthesises adenosine triphosphate (ATP), thanks to X-ray crystallography and pulsed-laser methods. However, 'moving' pictures should offer scientists a much clearer view of the enzyme's inner workings.