Specialised germanium surface as universal protein adapter
Specialised germanium surface as universal protein adapter - Researchers at the Ruhr Universität Bochum have developed a new method for attaching proteins to the surface of germanium crystals -- for the first time also membrane proteins. This enables time-resolved tracking of the interactions between molecules using infrared spectroscopy in a way that is accurate down to atomic resolution. The method is applied in the EU project "Kinetics for Drug Discovery, K4DD," in which scientists explore the interplay of drugs and their interaction partners. With the new technology, the researchers can also study so-called G-protein-coupled receptors, which are the site of action for many drugs.(10.1021/ja400253p)
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