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Novel drug candidates offer new route to controlling inflammation - Pursuing a relatively untapped route for regulating the immune system, an international team of researchers has designed and conducted initial tests on molecules that have the potential to treat diseases involving inflammation, such as asthma, rheumatoid arthritis, stroke and sepsis. Reference: C. A. Floudas et al, 'De Novo Peptide Design with C3a Receptor Agonist and Antagonist Activities: Theoretical Predictions and Experimental Validation,' J. Med. Chem., 2012, 55 (9), pp 4159–4168 DOI: 10.1021/jm201609k