New proteins to clear the airways in cystic fibrosis and COPD

New proteins to clear the airways in cystic fibrosis and COPD - Scientists discovered a new strategy to help CF and COPD patients clear the thick and sticky mucus clogging their lungs, leading to life-threatening infections. The report online in the FASEB Journal shows the "SPLUNC1" protein and its derivative peptides may help thin mucus by affecting the epithelial sodium channel. Along with its implications for cystic fibrosis and COPD, the research enhances the understanding of hypertension due to its role in controlling blood pressure. Reference: 'Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways,' FASEB J, doi:10.1096/fj.12-207431 ; http://www.fasebj.org/content/early/2012/07/13/fj.12-207431.abstract