Chiral separation with microflows

Chiral separation with microflows – How do you separate enantiomers without any kind of chiral recognition between molecules? The answer it seems is to use asymmetric flow in a micro-fluidic channel. According to computer simulations run by scientists in Germany and Sweden, particles will move to different regions of the channel according to their chirality. Once there, they will migrate at different speeds, and thus they can be separated. The researchers say that this approach could lead to significant benefits in the pharmaceutical industry, where chiral separation plays a significant role in drug design. Reference: S Meinhardt et al, Phys. Rev. Lett., 2012, 108, 214504, DOI: 10.1103/PhysRevLett.108.21450